Laboratory of Biophysics and Evolution

Philippe Nghe and Paul Rainey are delighted to announce a new collaborative venture at the interface between biophysics and evolution with particular focus on the major evolutionary transitions, starting this July 2021.

LBE is directed by Philippe Nghe and is part of UMR CNRS-ESPCI 8231 Chemistry, Biology and Innovation. Paul Rainey is also Director of the Department of Microbial Population Biology at the Max-Planck Institute for Evolutionary Biology in Germany.

The newly formed Laboratory of Biophysics and Evolution aims to tackle some of the most fascinating questions in evolutionary biology:

  • -How does life originate?
  • -How does biological complexity evolve?
  • -Can we predict, and maybe even orient, the course of evolution?

Topics of investigation include origins of life, origins of cells and origins of multicellularity; the evolution of gene regulation, life cycles, heredity and communities.

Research within LBE aims for mechanistic understanding and draws from:

  • -experimental evolution
  • -molecular biology, biochemistry and analytical genetics
  • -screening technologies encompassing molecules and compartments (microfluidics, deep sequencing and image analysis).
  • -quantitative analysis and modeling
  • -philosophy of science applied to evolution

LBE comprises four teams:

  • -team Nghe: origins of life, (bio)chemical reaction networks, evolution of gene networks, microfluidic technologies
  • -team Rainey: fraternal transitions and the evolution of life cycles, egalitarian transitions and the evolution of heredity, eco-evolution dynamics of bacterial communities, millifluidic technologies
  • -team Molecular Self-Assembly (dir. Tommaso Fraccia)
  • -team Microfluidics MEMs et Nanostructures (dir. Patrick Tabeling)

For more details, go to our Research page.